Complex CCKBR:GAST map
Complex composition:

  1. GAST map
  2. CCKBR map

CCKBR:​GAST@Cytosol

Identifiers
NAME:CCKBR:GAST

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
 Cancer Associated Fibroblasts  map  / GROWTH_FACTORS_SIGNALING_PATHWAYS  map

References
ca_re278( Cancer Associated Fibroblasts  map ):
PMID:16713974
TLR signaling activates and IFNG inhibits PI3K pathway
PMID:11907067, PMID:15536084
SYK kinaze directly interacts with PI3K(p85) and activates perforin ??granule movement and polarization via PI3K /RAC1/PAK1/MEK??/ERK pathway
PMID:10426994??
Phosphorylated DAP10 directly interacts with regulatory subunit (p85) of PI3K and activates downstream pathway.
ca_re622( Cancer Associated Fibroblasts  map ):
PMID:9535722
IL13 induces phosporylation of IRS2 and PLCG1 which is probably a PLC responsible for downstream IL13 dependent Ca2+??mobilization signaling and assosiation of IRS2 and PLCG1
PMID:7890616
PCL (probably PCLG1) induces t hydrolysis of phosphoinositides and activates InsP3-induced intracellular Ca2+??release downstream of IL13.

Modifications:
Participates in complexes:
In compartment: Cytosol
  1. CCKBR:​GAST@Cytosol map
Participates in reactions:
As Reactant or Product:
  1. GAST@default map + CCKBR@Cytosol map → map CCKBR:​GAST@Cytosol map
As Catalyser:
  1. PI3KR(p85)*@Cytosol map → map PI3KR(p85)*@Cytosol map
  2. PLCG1@Cytosol map → map PLCG1|​pho@Cytosol map