Complex BIRC5:HBXIP map
Complex composition:

  1. HBXIP map
  2. BIRC5 map


BIRC5|​T34_pho:​HBXIP@Cytosol

Identifiers
NAME:BIRC5:HBXIP

References
rc_re668( Regulated Cell Death  map ):
PMID:12773388
in vitro survivin_BIRC5 alone does not suppress CASP3/7/9 activities
in HepG2, interaction by coIP of endogenous proteins
in HEK293 or in vitro, preferential binding to T34 phosphorylated BIRC5, as determined through the use of unphosphorylatable or phosphomimetic mutants
in Hela expression of a dominant negative CDC2 decreases interaction
rc_re484( Regulated Cell Death  map ):
PMID:15210107
reviews the differerent hypothesis concerning the biochemical events leading to activation of CASP9
in vitro, survivin and HBXIP together inhibits CASP9 processing and activation
in HT1080 cells, coexpression of BIRC5 and HBXIP suppresses staurosporin-induced apoptosis
in cell extracts from Hela transfected with siRNA against HBXIP, CYCS induced caspase activation is suppressed
PMID:10329646
by NOD1


Modifications:
Participates in complexes:
In compartment: Cytosol
  1. BIRC5|​T34_pho:​HBXIP@Cytosol map
Participates in reactions:
As Reactant or Product:
  1. HBXIP@Cytosol map + BIRC5|​T34_pho@Cytosol map map BIRC5|​T34_pho:​HBXIP@Cytosol map
As Catalyser:
  1. Caspase9*@Cytosol map map cleaved~Caspase9*@Cytosol map