Protein HBXIP map

Identifiers
late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
HUGO:LAMTOR5 HGNC:17955 ENTREZ:10542 UNIPROT:O43504

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / APOPTOSIS  map
 Regulated Cell Death  map  / CASPASES  map

HBXIP@Cytosol

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / APOPTOSIS  map
 Regulated Cell Death  map  / CASPASES  map

References
rc_re668( Regulated Cell Death  map ):
PMID:12773388
in vitro survivin_BIRC5 alone does not suppress CASP3/7/9 activities
in HepG2, interaction by coIP of endogenous proteins
in HEK293 or in vitro, preferential binding to T34 phosphorylated BIRC5, as determined through the use of unphosphorylatable or phosphomimetic mutants
in Hela expression of a dominant negative CDC2 decreases interaction

Modifications:
In compartment: Cytosol
  1. HBXIP@Cytosol map
Participates in complexes:
In compartment: Cytosol
  1. BIRC5|​T34_pho:​HBXIP@Cytosol map
Participates in reactions:
As Reactant or Product:
  1. HBXIP@Cytosol map + BIRC5|​T34_pho@Cytosol map → map BIRC5|​T34_pho:​HBXIP@Cytosol map
As Catalyser:
  1. Caspase9*@Cytosol map → map cleaved~Caspase9*@Cytosol map