References
PMID:20103683
in head and neck squamous cell carcinoma cells, enhanced TKTL1 expression and promoter hypomethylation
TKTL1 overexpression associated with increased growth
increase in F6P and glyceraldehyde-3P
increase in glycolysis in a HIF1 dependent manner
they propose that TKTL1 promotes F6P and glyceraldehyde 3P, displayed here as the reverse reaction