Gene HK2 map

Identifiers
HUGO:HK2
hexokinase 2
HUGO:HK2 HGNC:4923 ENTREZ:3099 UNIPROT:P52789

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
 Cancer Associated Fibroblasts  map  / METABOLIC  map
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
 Regulated Cell Death  map  / APOPTOSIS  map
 Regulated Cell Death  map  / STARVATION_AUTOPHAGY  map
 Regulated Cell Death  map  / GLUCOSE_METABOLISM  map
 Regulated Cell Death  map  / MITOCHONDRIAL_METABOLISM  map
 Regulated Cell Death  map  / MOMP_REGULATION  map
 Regulated Cell Death  map  / NECROPTOSIS  map

References
PMID:25732824
Hexokinase 2 is upregulated in CAFs downstream of HIF1A
PMID:9436976
HK2 id e dicrect target of HIF1A

gHK2@Nucleus

Maps_Modules
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
 Regulated Cell Death  map  / APOPTOSIS  map
 Regulated Cell Death  map  / STARVATION_AUTOPHAGY  map
 Regulated Cell Death  map  / GLUCOSE_METABOLISM  map
 Regulated Cell Death  map  / MITOCHONDRIAL_METABOLISM  map
 Regulated Cell Death  map  / MOMP_REGULATION  map
 Regulated Cell Death  map  / NECROPTOSIS  map

References
rc_re158( Regulated Cell Death  map ):
Reaction (id=re340, name=; 10 01 04.xml)
PMID:11557773
by HIF1
PMID:14672622
in liver tumors by HIF1
PMID:16782875
by MLX:MLXIP

Modifications:
In compartment: Cytosol
  1. gHK2@Cytosol map
In compartment: Nucleus
  1. gHK2@Nucleus map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. gHK2@Cytosol map → map rHK2@Cytosol map
    2. gHK2@Nucleus map → map rHK2@Nucleus map
    As Catalyser: