Identifiers
ZEB1_ZEB2*
zinc finger E-box binding homeobox 1
HUGO:ZEB1, HGNC:11642, ENTREZ:6935, GENECARDS:GC10P031648
zinc finger E-box binding homeobox 2
HUGO:ZEB2, HGNC:14881, ENTREZ:9839, GENECARDS:GC02M145145
Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
EMT Senescence / EMT_REGULATORS
References
PMID:20706219
ZEB1 and ZEB2 are targeted by all MIR200 family members.
References
em_emtc_emtc_re1115( EMT Senescence ):
PMID:22945800
PMID:22286765
Six1 induces ZEB1 and EMT through transcriptional repression of miR200.
PMID:22311119
miR-200b regulates ZEB2 expression and thus controls metastasis in gastric cancer