Protein FTH1 map

Identifiers
ferritin, heavy polypeptide 1
HUGO:FTH1 HGNC:3976 ENTREZ:2495 UNIPROT:P02794

Maps_Modules
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
 Regulated Cell Death  map  / STARVATION_AUTOPHAGY  map
 Regulated Cell Death  map  / DEATH_RECEPTOR_PATHWAYS  map
 Regulated Cell Death  map  / MITOCHONDRIAL_METABOLISM  map
 Regulated Cell Death  map  / NECROPTOSIS  map
 Regulated Cell Death  map  / FERROPTOSIS  map

References
PMID:17603935
Ferritin is an iron storage protein and its concentration is inversely related to the level of Labile Iron Pool.

FTH1@Cytosol

Maps_Modules
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
 Regulated Cell Death  map  / STARVATION_AUTOPHAGY  map
 Regulated Cell Death  map  / DEATH_RECEPTOR_PATHWAYS  map
 Regulated Cell Death  map  / MITOCHONDRIAL_METABOLISM  map
 Regulated Cell Death  map  / NECROPTOSIS  map

References
rc_re1537:( Regulated Cell Death  map ) Tumor necrosis factor-alpha-induced reactive oxygen species formation is mediated by JNK1-dependent ferritin degradation and elevation of labile iron pool.
rc_re1539( Regulated Cell Death  map ):
PMID:17603935
Tumor necrosis factor-alpha-induced reactive oxygen species formation is mediated by JNK1-dependent ferritin degradation and elevation of labile iron pool.

Modifications:
In compartment: Cytosol
  1. FTH1@Cytosol map
Participates in complexes:
In compartment: Cytosol
  1. FTH1:​FTL@Cytosol map
  2. FTH1:​FTL:​Fe2+@Cytosol map
Participates in reactions:
As Reactant or Product:
  1. FTH1@Cytosol map → map degraded
  2. rFTH1@Nucleus map → map FTH1@Cytosol map
  3. Fe2+@Cytosol map + FTH1:​FTL@Cytosol map → map FTH1:​FTL:​Fe2+@Cytosol map
As Catalyser:
  1. Fe2+@Cytosol map → map Intracellular sequestering~of iron ion@Cytosol map
  2. Fe2+@Cytosol map → map Intracellular sequestering~of iron ion@Cytosol map