Reaction state_transition rc_re1537
Fe2+@Cytosol
→ Intracellular sequestering~of iron ion@Cytosol
Reaction regulators:
- Boolean_logic_gate_and
- FTH1@Cytosol
and FTL@Cytosol
- Catalysis
- FTH1@Cytosol
- FTL@Cytosol
References
Tumor necrosis factor-alpha-induced reactive oxygen species formation is mediated by JNK1-dependent ferritin degradation and elevation of labile iron pool.