Identifiers
NADH dehydrogenase (ubiquinone) complex I, assembly factor 2
HUGO:NDUFAF2 HGNC:28086 ENTREZ:91942 UNIPROT:Q8N183
Maps_Modules
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
Regulated Cell Death / ANTIOXIDANT_RESPONSE
Regulated Cell Death / MITOCHONDRIAL_GENES
Regulated Cell Death / MITOCHONDRIAL_METABOLISM
Regulated Cell Death / OXIDATIVE_PHOSPHOYLATION_AND_TCA_CYCLE
Maps_Modules
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
Regulated Cell Death / ANTIOXIDANT_RESPONSE
Regulated Cell Death / MITOCHONDRIAL_GENES
Regulated Cell Death / MITOCHONDRIAL_METABOLISM
Regulated Cell Death / OXIDATIVE_PHOSPHOYLATION_AND_TCA_CYCLE
References
rc_re69( Regulated Cell Death ):
PMID:16200211
NDUFAF2
PMID:17344420
ECSIT:NDUFAF1
PMID:20816094
involvement of ACAD9 in the ECSIT:NDUFAF1 complex
PMID:16218961
NDUFAF1
PMID:15526035
AIF deficient cells exhibit a decrease content of complex I. It was proposed that AIF has a role in the biogenesis or maintenance of complex I
PMID:20025615
comprehensive review about complex I
+ MT-ND5@Mitochondrial inner membrane + MT-ND4@Mitochondrial inner membrane + MT-ND4L@Mitochondrial inner membrane + MT-ND3@Mitochondrial inner membrane + MT-ND2@Mitochondrial inner membrane + MT-ND1@Mitochondrial inner membrane + MT-ND6@Mitochondrial inner membrane → FMN:MT-ND1:MT-ND2:MT-ND3:MT-ND4:MT-ND4L:MT-ND5:MT-ND6:NDUFA1:NDUFA10:NDUFA11:NDUFA12:NDUFA13:NDUFA2:NDUFA3:NDUFA4:NDUFA5:NDUFA6:NDUFA7:NDUFA8:NDUFA9:NDUFAB1:NDUFB1:NDUFB10:NDUFB11:NDUFB2:NDUFB3:NDUFB4:NDUFB5:NDUFB6:NDUFB7:NDUFB8:NDUFB9:NDUFC1:NDUFC2:NDUFS1|[2Fe-2S],[4Fe-4S],[4Fe-4S]:NDUFS2:NDUFS3:NDUFS4:NDUFS5:NDUFS6:NDUFS7|[4Fe-4S]:NDUFS8|[4Fe-4S],[4Fe-4S]:NDUFV1|[4Fe-4S]:NDUFV2|[2Fe-2S]:NDUFV3@Mitochondrial inner membrane