Protein SIRT1 map

Identifiers
sirtuin 1
HUGO:SIRT1 HGNC:14929 ENTREZ:23411 UNIPROT:Q96EB6

Maps_Modules
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
 Regulated Cell Death  map  / DEATH_RECEPTOR_PATHWAYS  map
 Regulated Cell Death  map  / DNA_DAMAGE_RESPONSE  map
 Regulated Cell Death  map  / FATTY_ACID_BIOSYNTHESIS  map
 Regulated Cell Death  map  / MITOCHONDRIAL_METABOLISM  map
 Regulated Cell Death  map  / RCD_GENES  map
 Regulated Cell Death  map  / PENTOSE_PHOSPHATE_PATHWAY  map

SIRT1@Cytosol

Maps_Modules
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
 Regulated Cell Death  map  / DEATH_RECEPTOR_PATHWAYS  map
 Regulated Cell Death  map  / DNA_DAMAGE_RESPONSE  map
 Regulated Cell Death  map  / FATTY_ACID_BIOSYNTHESIS  map
 Regulated Cell Death  map  / MITOCHONDRIAL_METABOLISM  map
 Regulated Cell Death  map  / RCD_GENES  map
 Regulated Cell Death  map  / PENTOSE_PHOSPHATE_PATHWAY  map

SIRT1@Nucleus

Maps_Modules
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
 Regulated Cell Death  map  / DEATH_RECEPTOR_PATHWAYS  map
 Regulated Cell Death  map  / DNA_DAMAGE_RESPONSE  map
 Regulated Cell Death  map  / FATTY_ACID_BIOSYNTHESIS  map
 Regulated Cell Death  map  / MITOCHONDRIAL_METABOLISM  map
 Regulated Cell Death  map  / RCD_GENES  map
 Regulated Cell Death  map  / PENTOSE_PHOSPHATE_PATHWAY  map

References
rc_re469:( Regulated Cell Death  map ) PMID:18687677
rc_re472( Regulated Cell Death  map ):
PMID:15205477
in 293T cells Sirt1 attenuates BAX mediated apoptosis by deacetylating Ku70
identification of acetylation sites on Ku70 by use of synthetic acetylated peptides
rc_re907:( Regulated Cell Death  map ) PMID:15744310
rc_re1127( Regulated Cell Death  map ):
PMID:19590512
Siva1 and mdm2
PMID:15989956
HUWE1
PMID:19960022
effect of SIRT1 K382-deacetylation


Modifications:
In compartment: Cytosol
  1. SIRT1@Cytosol map
In compartment: Nucleus
  1. SIRT1@Nucleus map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. rSIRT1@Nucleus map map SIRT1@Cytosol map
    2. SIRT1@Cytosol map map SIRT1@Nucleus map
    3. rSIRT1@Nucleus map map SIRT1@Cytosol map
    As Catalyser:
    1. ACSS2|​ace@Cytosol map map ACSS2@Cytosol map
    2. p53*|​S15_pho|​active@Nucleus map map p53*@Nucleus map
    3. STK11|​K48_ace|​T366_unk@Nucleus map map STK11|​T366_unk@Nucleus map
    4. Ku70*|​K539_ace|​K542_ace@Nucleus map map Ku70*@Nucleus map
    5. PPARGC1A|​ace@Nucleus map map PPARGC1A@Nucleus map