Protein SESN1 map

Identifiers
sestrin 1
HUGO:SESN1 HGNC:21595 ENTREZ:27244 UNIPROT:Q9Y6P5

Maps_Modules
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
 Regulated Cell Death  map  / STARVATION_AUTOPHAGY  map
 Regulated Cell Death  map  / CASPASES  map
 Regulated Cell Death  map  / FATTY_ACID_BIOSYNTHESIS  map
 Regulated Cell Death  map  / MITOCHONDRIAL_METABOLISM  map
 Regulated Cell Death  map  / RCD_GENES  map

SESN1@Cytosol

Maps_Modules
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
 Regulated Cell Death  map  / STARVATION_AUTOPHAGY  map
 Regulated Cell Death  map  / CASPASES  map
 Regulated Cell Death  map  / FATTY_ACID_BIOSYNTHESIS  map
 Regulated Cell Death  map  / MITOCHONDRIAL_METABOLISM  map
 Regulated Cell Death  map  / RCD_GENES  map

References
rc_re334( Regulated Cell Death  map ):
PMID:15509864
review
PMID:16054095
by CAMKK2
PMID:16054096
PMID:17244528
by calcium via CAMKK2 and AMPK
PMID:15980064
by CAMKK
PMID:18692468
propose that SESN2 promotes AMPK autophosphorylation, thus increasing TSC1/2 activity.
PMID:19197243
in RPE1-hTERT mouse inner medullary collecting duct cells, in MEFs, in MCF10A, by TAK1, upon TRAIL exposure
in MCF10A upon Ca2+ by CAMKK2
High Calcium lvl activate CAMKK2 enzyme and leads to AMPK activation
PMID:19037093PMID:17244528
PMID:20484410

Modifications:
In compartment: Cytosol
  1. SESN1@Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. rSESN1@Nucleus map → map SESN1@Cytosol map
    As Catalyser:
    1. AMP:​PKA_R*:​PRKAA*:​PRKAG*@Cytosol map → map AMP:​PKA_R*:​PRKAA*|​T172_pho:​PRKAG*@Cytosol map