Protein 4E-BP* map

Identifiers
eukaryotic translation initiation factor 4E binding protein 1
HUGO:EIF4EBP1 HGNC:3288 ENTREZ:1978 UNIPROT:Q13541
HUGO:EIF4EBP1 HGNC:3288 ENTREZ:1978 UNIPROT:Q13541 GENECARDS:EIF4EBP1 REACTOME:84152 KEGG:1978 ATLASONC:EIF4EBP1ID40432ch8p12 WIKI:EIF4EBP1

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / STARVATION_AUTOPHAGY  map
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / PI3K_AKT_MTOR  map

References
PMID:25682865
Autophagy through 4EBP1 and AMPK regulates oxidative stress-induced premature senescence in auditory cells
PMID:19339977
PMID:15314020
PMID:12709531

4E-BP*@Cytosol

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / STARVATION_AUTOPHAGY  map

References
rc_re377( Regulated Cell Death  map ):
PMID:9465032
PMID:15690031

4E-BP*|​pho@Cytosol

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / STARVATION_AUTOPHAGY  map

References
rc_re377( Regulated Cell Death  map ):
PMID:9465032
PMID:15690031

4E-BP*|​T37_pho|​T46_pho|​S65_pho|​T70_pho@Cytoplasm

References
s_akt1_re66:( Survival  map ) PMID:16286006

Modifications:
In compartment: Cytoplasm
  1. 4E-BP*|​T37_pho|​T46_pho|​S65_pho|​T70_pho@Cytoplasm map
In compartment: Cytosol
  1. 4E-BP*@Cytosol map
  2. 4E-BP*|​pho@Cytosol map
Participates in complexes:
In compartment: Cytoplasm
  1. 4E-BP*:​EIF3*:​EIF4E*:​M7GTP*:​mRNA generic*:​p70_alpha_*@Cytoplasm map
  2. 4E-BP*:​EIF3*:​EIF4E*:​M7GTP*:​MLST8:​MTOR|​S1261_pho|​emp|​S2481_pho:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho:​mRNA generic*:​p70_alpha_*|​T389_pho@Cytoplasm map
In compartment: Cytosol
  1. 4E-BP*:​EIF4E@Cytosol map
Participates in reactions:
As Reactant or Product:
  1. 4E-BP*@Cytosol map → map 4E-BP*|​pho@Cytosol map
  2. EIF4E@Cytosol map + 4E-BP*@Cytosol map → map 4E-BP*:​EIF4E@Cytosol map
  3. (MLST8:​MTOR|​S1261_pho|​S2481_pho:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho)|​active@Cytoplasm map + 4E-BP*:​EIF3*:​EIF4E*:​M7GTP*:​mRNA generic*:​p70_alpha_*@Cytoplasm map → map 4E-BP*:​EIF3*:​EIF4E*:​M7GTP*:​MLST8:​MTOR|​S1261_pho|​emp|​S2481_pho:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho:​mRNA generic*:​p70_alpha_*|​T389_pho@Cytoplasm map
  4. 4E-BP*:​EIF3*:​EIF4E*:​M7GTP*:​MLST8:​MTOR|​S1261_pho|​emp|​S2481_pho:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho:​mRNA generic*:​p70_alpha_*|​T389_pho@Cytoplasm map → map EIF3*:​EIF4E*:​M7GTP*:​MLST8:​MTOR|​S1261_pho|​emp|​S2481_pho:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho:​mRNA generic*@Cytoplasm map + p70_alpha_*|​T389_pho@Cytoplasm map + 4E-BP*|​T37_pho|​T46_pho|​S65_pho|​T70_pho@Cytoplasm map
As Catalyser: