Protein ACHE map

Identifiers
acetylcholinesterase
HUGO:ACHE HGNC:108 ENTREZ:43 UNIPROT:P22303

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / APOPTOSIS  map
 Regulated Cell Death  map  / CASPASES  map
 RECON2  map

References
PMID:22514517

ACHE@Cytosol

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / APOPTOSIS  map
 Regulated Cell Death  map  / CASPASES  map

References
rc_re482( Regulated Cell Death  map ):
PMID:17377525
review on apoptosome formation
PMID:11864614
stoechiometry apoptosome
PMID:12522243
inhibition of apoptosome formation by prothymosin-alpha
PMID:15087373
in HT-29 colon adenocarcinoma cells, siRNA against ACHE prevents the APAF1:CYCS interaction and etoposide-induced
PMID:14622304
AFP positive influence on apoptosome assembly
PMID:18439902
CAS PHAPI and HSP70 enhance apoptosome formation and caspase activation

Modifications:
In compartment: Cytosol
  1. ACHE@Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
      As Catalyser:
      1. Cytochrome_C*|​ferroheme@Cytosol map + (d)ATP@Cytosol map + APAF1@Cytosol map → map (d)ATP:​APAF1:​Cytochrome_C*|​ferroheme@Cytosol map