Protein PIK3C3 map

Identifiers
phosphatidylinositol 3-kinase, catalytic subunit type 3
HUGO:PIK3C3 HGNC:8974 ENTREZ:5289 UNIPROT:Q8NEB9

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / APOPTOSIS  map
 Regulated Cell Death  map  / STARVATION_AUTOPHAGY  map
 Regulated Cell Death  map  / DEATH_RECEPTOR_PATHWAYS  map

References
PMID:22421439
PMID:28645028

PIK3C3@Cytosol

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / APOPTOSIS  map
 Regulated Cell Death  map  / STARVATION_AUTOPHAGY  map
 Regulated Cell Death  map  / DEATH_RECEPTOR_PATHWAYS  map

References
rc_re650( Regulated Cell Death  map ):
in vitro by CASP3, CASP7, CASP8
in Ba/F3 upon IL3 deprivation, in FDCP1 upon IL3 deprivation, in U937 upon serum starvation, z-VAD-fmk inhibitable cleavagePMID:23377657
rc_re1762( Regulated Cell Death  map ):
PMID:23725295
PMID:17106237
PMID:22885520
PMID:18612260

Modifications:
In compartment: Cytosol
  1. PIK3C3@Cytosol map
Participates in complexes:
In compartment: Autopagosome
  1. ATG14:​BECN1|​ubi:​PIK3C3:​PIK3R4:​UVRAG@Autopagosome map
Participates in reactions:
As Reactant or Product:
  1. BECN1|​ubi@Cytosol map + PIK3C3@Cytosol map + ATG14@Cytosol map + UVRAG@Cytosol map + PIK3R4@Cytosol map → map ATG14:​BECN1|​ubi:​PIK3C3:​PIK3R4:​UVRAG@Autopagosome map
  2. PIK3C3@Cytosol map → map cleaved~PIK3C3*@Cytosol map
As Catalyser:
  1. PIP2@Autopagosome map → map PIP3*@Autopagosome map
  2. Autophagosome initiation@Autopagosome map → map Autophagosome formation@Autopagosome map