Protein NICD co-factors* map

Identifiers
NICD-cofactors*
recombination signal binding protein for immunoglobulin kappa J region
HUGO:RBPJ, HGNC:5724, ENTREZ:3516, UNIPROT:Q06330 , GENECARDS:GC04P026165
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HUGO:HIF1A, HGNC:4910, ENTREZ:3091, GENECARDS:GC14P062162, UNIPROT:Q16665
axin 1
HUGO:AXIN1, HGNC:903, ENTREZ:8312, UNIPROT:O15169??, GENECARDS:GC16M000338
catenin (cadherin-associated protein), beta 1, 88kDa
HUGO:CTNNB1, HGNC:2514, ENTREZ:1499, UNIPROT:P35222, GENECARDS:GC03P041236

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence  map  / EMT_REGULATORS  map

References
PMID:21828089
These proteins synergizes with NICD on Notch target genes.

Modifications:
In compartment: Nucleus
  1. NICD co-factors*@Nucleus map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. NICD co-factors*@Nucleus map → map CBF1*@Nucleus map
    2. NICD co-factors*@Nucleus map → map HIF_alpha_*@Cytosol map
    3. NICD co-factors*@Nucleus map → map _beta_-Catenin*@Cytosol map
    4. NICD co-factors*@Nucleus map → map AXIN1@Cytosol map
    As Catalyser: