Identifiers
Laminin 1*
laminin, alpha 1
HUGO:LAMA1 HGNC:6481 ENTREZ:284217 UNIPROT:P25391
laminin, beta 1
CLM, "cutis laxa with marfanoid phenotype"
HUGO:LAMB1 HGNC:6486 ENTREZ:3912 UNIPROT:P07942
laminin, gamma 1
HUGO:LAMC1 HGNC:6492 ENTREZ:3915 UNIPROT:P11047

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence   / EMT_REGULATORS 
 EMT Senescence   / CELL_MATRIX_ADHESIONS 
 EMT Senescence   / ECM 

References
PMID:114518
Laminin-1: LAMA1, LAMB1, LAMC1

References
em_emtc_emtc_re910( EMT Senescence  ):
PMID:19161977
In the endoplasmic reticulum, integrin subunits find their binding partners and form heterodimers.
Monomeric integrins never reach the cell surface.
Integrins a1b1, a2b1, a10b1 and a11b1 bind to collagens
PMID:12297042
Cell adhesion to components of the ECM is important in the angiogenesis
PMID:2153105
PMID:2786007
PMID:7639691
PMID:10809728
integrins are receptors for different ECM proteins: Collagen 1, 4; Laminin 1, 8; Fibronectin and Vitronectin
PMID:7522194
PMID:16195317
Interactions between integrins and the ECM proteins result in focal cell adhesion and cytoskeleton remodeling.

1. Laminin1*@Extracellular space

1. Laminin1*:​a2b1*_a3b1*@Extracellular space
2. Laminin 1 partners*:​Laminin1*@Extracellular space

1. Galectin 3 partners*@Extracellular space → Laminin1*@Extracellular space
2. Laminin1*@Extracellular space → Truncated Laminin1*@Extracellular space
3. Laminin1*@Extracellular space + Laminin 1 partners*@Extracellular space → Laminin 1 partners*:​Laminin1*@Extracellular space
4. Elastin partners*@Extracellular space → Laminin1*@Extracellular space
5. Laminin 1 partners*:​Laminin1*@Extracellular space → Cell-matrix adhesions@Extracellular space
6. a2b1*_a3b1*@Extracellular space + Laminin1*@Extracellular space → Laminin1*:​a2b1*_a3b1*@Extracellular space
7. LAMA1@Cytosol + LAMB1@Cytosol + LAMC1@Cytosol → Laminin1*@Extracellular space
8. Laminin1*:​a2b1*_a3b1*@Extracellular space → Cell-matrix adhesions@Extracellular space