Protein c-MET* map

Identifiers
met proto-oncogene
synonym "hepatocyte growth factor receptor", HGFR
HUGO:MET HGNC:7029 ENTREZ:4233 UNIPROT:P08581

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence  map  / EMT_REGULATORS  map
 EMT Senescence  map  / ECM  map

References
RTKs exist as inactive monomers; after binding to their ligands they form dimers and their intracellular domains are activated.
PMID:17496910
PMID:22128289

Modifications:
In compartment: Cytosol
  1. c-MET*@Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. RTK*@Cytosol map → map c-MET*@Cytosol map
    2. HGF@Extracellular space map + c-MET*@Cytosol map + c-MET*@Cytosol map → map em_emtc_emtc_s4814
    As Catalyser: