Protein FTL map

Identifiers
ferritin, light polypeptide
HUGO:FTL HGNC:3999 ENTREZ:2512 UNIPROT:P02792

Maps_Modules
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
 Regulated Cell Death  map  / STARVATION_AUTOPHAGY  map
 Regulated Cell Death  map  / DEATH_RECEPTOR_PATHWAYS  map
 Regulated Cell Death  map  / MITOCHONDRIAL_METABOLISM  map
 Regulated Cell Death  map  / NECROPTOSIS  map
 Regulated Cell Death  map  / FERROPTOSIS  map

References
PMID:27048822
PMID:26653790
PMID:26794443

FTL@Cytosol

Maps_Modules
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
 Regulated Cell Death  map  / STARVATION_AUTOPHAGY  map
 Regulated Cell Death  map  / DEATH_RECEPTOR_PATHWAYS  map
 Regulated Cell Death  map  / MITOCHONDRIAL_METABOLISM  map
 Regulated Cell Death  map  / NECROPTOSIS  map

References
rc_re1537:( Regulated Cell Death  map ) Tumor necrosis factor-alpha-induced reactive oxygen species formation is mediated by JNK1-dependent ferritin degradation and elevation of labile iron pool.
rc_re1538( Regulated Cell Death  map ):
PMID:17603935
Tumor necrosis factor-alpha-induced reactive oxygen species formation is mediated by JNK1-dependent ferritin degradation and elevation of labile iron pool.

Modifications:
In compartment: Cytosol
  1. FTL@Cytosol map
Participates in complexes:
In compartment: Cytosol
  1. FTH1:​FTL@Cytosol map
  2. FTH1:​FTL:​Fe2+@Cytosol map
Participates in reactions:
As Reactant or Product:
  1. FTL@Cytosol map → map degraded
  2. Fe2+@Cytosol map + FTH1:​FTL@Cytosol map → map FTH1:​FTL:​Fe2+@Cytosol map
As Catalyser:
  1. Fe2+@Cytosol map → map Intracellular sequestering~of iron ion@Cytosol map
  2. Fe2+@Cytosol map → map Intracellular sequestering~of iron ion@Cytosol map