Identifiers
zinc finger E-box binding homeobox 2
HUGO:ZEB2, HGNC:14881, ENTREZ:9839, UNIPROT:O60315, GENECARDS:GC02M145145
Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
EMT Senescence / EMT_REGULATORS
References
PMID:19839049
Feedback loops
PMID:225147423
Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
EMT Senescence / EMT_REGULATORS
References
PMID:19839049
Feedback loops
PMID:225147423
em_emtc_emtc_re356( EMT Senescence ):
PMID:22945800
PMID:22286765
Six1 induces ZEB1 and EMT through transcriptional repression of miR200.
PMID:20706219
Feedback loop between ZEB1, ZEB2 and MIR200 family
PMID:19935649
ZEB1 inhibits expression of MIR200 family
PMID:22514743
SNAI1 represses expression of all MIR200 family members.
em_emtc_emtc_re366( EMT Senescence ):
SNAI1 inhibits miR-203
SNAI1 represses miR-203 and miR-200b expression
PMID:21159887
p53 activates expression of miR-203
PMID:20702634
Feedback loop: ZEB1 inhibits expression of MIR203 and MIR183
ZEB1 directly controls transcription of the miR-203 and miR-183 and miR-200 family genes
ZEB2 inhibits expression of MIR203