Protein MED12
Identifiers
Mediator complex subunit 12
HUGO:MED12 HGNC:11957 ENTREZ:9968 UNIPROT:Q93074 GENECARDS:MED12 REACTOME:65526 KEGG:9968 ATLASONC:GC_MED12 WIKI:MED12
Maps_Modules
HMC:EVADING_GROWTH_SUPPRESSORS
Survival
/ HEDGEHOG
References
PMID:17000779
PMID:21330129
Mediator complex subunit
Modifications:
Participates in complexes:
In compartment: Nucleus
- CDK8:Core_promoter*:CyclinC*:MED12:MED13:Mediator*@Nucleus
- CBP*:CDK8:Core_promoter*:CyclinC*:GLI3-190*:MED12:MED13:Mediator*:promoter_region@Nucleus
Participates in reactions:
As Reactant or Product:- CDK8:Core_promoter*:CyclinC*:MED12:MED13:Mediator*@Nucleus
+ CBP*@Nucleus
+ gpromoter_region@Nucleus
+ GLI3-190*|unk|active@Nucleus
→
CBP*:CDK8:Core_promoter*:CyclinC*:GLI3-190*:MED12:MED13:Mediator*:promoter_region@Nucleus
As Catalyser:- gGLI1@Nucleus
→
rGLI1@Nucleus