Protein GLI3-190* map

Identifiers
Gli family zinc finger 3
HUGO:GLI3 HGNC:4319 ENTREZ:2737 UNIPROT:P10071 GENECARDS:GLI3 KEGG:2737 ATLASONC:GC_GLI3 WIKI:GLI3

Maps_Modules
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / HEDGEHOG  map

References
PMID:11001584

GLI3-190*|​S849_emp|​active@Primary Cilium

References
s_shh1_re77( Survival  map ):
PMID:20711444
PTM=sumoylation N/A in CellDesigner.
Sumoylation not detected on endogenous Gli proteins

GLI3-190*|​S849_emp|​S880_unk|​active@Primary Cilium

Maps_Modules
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / HEDGEHOG  map

References
PMID:20711444
PTM=sumoylation N/A in CellDesigner
s_shh1_re77( Survival  map ):
Sumoylation not detected on endogenous Gli proteins
s_shh1_re48( Survival  map ):
PMID:20360384
PMID:19996169
PMID:18559511
su_shh1_s_shh1_re77( Survival  map ):

GLI3-190*|​S849_emp|​S880_unk|​active@Nucleus

References
s_shh1_re48( Survival  map ):
PMID:20360384
PMID:19996169
PMID:18559511

GLI3-190*|​S849_pho|​S868_pho|​S907_pho|​S873_pho|​S852_pho|​S865_pho|​S877_pho|​S903_pho|​S860_pho|​S880_pho|​S910_pho|​S1006_pho|​S980_pho|​ubi|​ubi|​ubi|​ubi@Proteosome

References
s_shh1_re20( Survival  map ):
PMID17283082.
A domain in the a.a. sequence favors the truncation of the protein

GLI3-190*|​ubi|​ubi|​ubi|​ubi@Nucleus

References
s_shh2_re1:( Survival  map ) PMID:20360384 PMID:16740475

GLI3-190*|​unk|​active@Nucleus

References
s_shh2_re1:( Survival  map ) PMID:20360384 PMID:16740475
s_shh2_re64:( Survival  map ) PMID:19996099
s_shh2_re118:( Survival  map ) PMID:17000779

GLI3-190*|​unk|​pho|​active@Nucleus

References
s_shh2_re64:( Survival  map ) PMID:19996099

Modifications:
In compartment: Cytosol
  1. GLI3-190*|​S849_emp@Cytosol map
  2. GLI3-190*|​S849_pho|​S868_pho|​S907_pho|​S873_pho|​S852_pho|​S865_pho|​S877_pho|​S903_pho|​S860_pho|​S880_pho|​S910_pho|​S1006_pho|​S980_pho|​ubi|​ubi|​ubi|​ubi@Cytosol map
In compartment: Nucleus
  1. GLI3-190*|​unk|​active@Nucleus map
  2. GLI3-190*|​unk|​pho|​active@Nucleus map
  3. GLI3-190*|​S849_emp|​S880_unk|​active@Nucleus map
  4. GLI3-190*|​ubi|​ubi|​ubi|​ubi@Nucleus map
In compartment: Primary Cilium
  1. GLI3-190*|​S849_emp|​active@Primary Cilium map
  2. GLI3-190*|​S849_emp|​S880_unk|​active@Primary Cilium map
In compartment: Proteosome
  1. GLI3-190*|​S849_pho|​S868_pho|​S907_pho|​S873_pho|​S852_pho|​S865_pho|​S877_pho|​S903_pho|​S860_pho|​S880_pho|​S910_pho|​S1006_pho|​S980_pho|​ubi|​ubi|​ubi|​ubi@Proteosome map
Participates in complexes:
In compartment: Cytosol
  1. GLI3-190*|​S849_emp:​SUFU:​ULK3@Cytosol map
  2. GLI3-190*|​S849_pho|​S907_pho|​S865_pho|​S877_pho|​S1006_pho|​S980_pho:​SUFU:​ULK3@Cytosol map
  3. GLI3-190*|​S849_pho|​S868_pho|​S907_pho|​S873_pho|​S852_pho|​S865_pho|​S877_pho|​S903_pho|​S860_pho|​S880_pho|​S910_pho|​S1006_pho|​S980_pho:​SUFU:​ULK3@Cytosol map
  4. GLI3-190*|​S849_pho|​S868_pho|​S907_pho|​S873_pho|​S852_pho|​S865_pho|​S877_pho|​S903_pho|​S860_pho|​S880_pho|​S910_pho|​S1006_pho|​S980_pho|​ubi|​ubi|​ubi|​ubi:​SUFU:​ULK3@Cytosol map
  5. GLI3-190*|​S849_emp:​KIF7:​SUFU:​ULK3@Cytosol map
In compartment: Nucleus
  1. GLI3-190*:​promoter_region@Nucleus map
  2. CBP*:​CDK8:​Core_promoter*:​CyclinC*:​GLI3-190*:​MED12:​MED13:​Mediator*:​promoter_region@Nucleus map
In compartment: Primary Cilium
  1. GLI3-190*|​S849_emp:​KIF7:​SUFU:​ULK3@Primary Cilium map
Participates in reactions:
As Reactant or Product:
  1. SUFU@Cytosol map + GLI3-190*|​S849_emp@Cytosol map + KIF7@Cytosol map + ULK3@Cytosol map → map GLI3-190*|​S849_emp:​KIF7:​SUFU:​ULK3@Cytosol map
  2. GLI3-190*|​S849_emp:​KIF7:​SUFU:​ULK3@Cytosol map → map GLI3-190*|​S849_emp:​KIF7:​SUFU:​ULK3@Primary Cilium map
  3. GLI3-190*|​S849_emp:​KIF7:​SUFU:​ULK3@Primary Cilium map → map SUFU@Primary Cilium map + GLI3-190*|​S849_emp|​active@Primary Cilium map + KIF7@Primary Cilium map + ULK3@Primary Cilium map
  4. GLI3-190*|​S849_emp|​active@Primary Cilium map → map GLI3-190*|​S849_emp|​active@Primary Cilium map
  5. GLI3-190*|​S849_emp|​S880_unk|​active@Primary Cilium map → map GLI3-190*|​S849_emp|​S880_unk|​active@Nucleus map
  6. SUFU@Cytosol map + GLI3-190*|​S849_emp@Cytosol map + ULK3@Cytosol map → map GLI3-190*|​S849_emp:​SUFU:​ULK3@Cytosol map
  7. GLI3-190*|​S849_emp:​SUFU:​ULK3@Cytosol map → map GLI3-190*|​S849_pho|​S907_pho|​S865_pho|​S877_pho|​S1006_pho|​S980_pho:​SUFU:​ULK3@Cytosol map
  8. GLI3-190*|​S849_pho|​S907_pho|​S865_pho|​S877_pho|​S1006_pho|​S980_pho:​SUFU:​ULK3@Cytosol map → map GLI3-190*|​S849_pho|​S868_pho|​S907_pho|​S873_pho|​S852_pho|​S865_pho|​S877_pho|​S903_pho|​S860_pho|​S880_pho|​S910_pho|​S1006_pho|​S980_pho:​SUFU:​ULK3@Cytosol map
  9. GLI3-190*|​S849_pho|​S868_pho|​S907_pho|​S873_pho|​S852_pho|​S865_pho|​S877_pho|​S903_pho|​S860_pho|​S880_pho|​S910_pho|​S1006_pho|​S980_pho|​ubi|​ubi|​ubi|​ubi:​SUFU:​ULK3@Cytosol map → map SUFU@Cytosol map + ULK3@Cytosol map + GLI3-190*|​S849_pho|​S868_pho|​S907_pho|​S873_pho|​S852_pho|​S865_pho|​S877_pho|​S903_pho|​S860_pho|​S880_pho|​S910_pho|​S1006_pho|​S980_pho|​ubi|​ubi|​ubi|​ubi@Cytosol map
  10. GLI3-190*|​S849_pho|​S868_pho|​S907_pho|​S873_pho|​S852_pho|​S865_pho|​S877_pho|​S903_pho|​S860_pho|​S880_pho|​S910_pho|​S1006_pho|​S980_pho|​ubi|​ubi|​ubi|​ubi@Cytosol map → map GLI3-190*|​S849_pho|​S868_pho|​S907_pho|​S873_pho|​S852_pho|​S865_pho|​S877_pho|​S903_pho|​S860_pho|​S880_pho|​S910_pho|​S1006_pho|​S980_pho|​ubi|​ubi|​ubi|​ubi@Proteosome map
  11. GLI3-190*|​S849_pho|​S868_pho|​S907_pho|​S873_pho|​S852_pho|​S865_pho|​S877_pho|​S903_pho|​S860_pho|​S880_pho|​S910_pho|​S1006_pho|​S980_pho:​SUFU:​ULK3@Cytosol map → map GLI3-190*|​S849_pho|​S868_pho|​S907_pho|​S873_pho|​S852_pho|​S865_pho|​S877_pho|​S903_pho|​S860_pho|​S880_pho|​S910_pho|​S1006_pho|​S980_pho|​ubi|​ubi|​ubi|​ubi:​SUFU:​ULK3@Cytosol map
  12. GLI3-190*|​S849_emp|​active@Primary Cilium map → map GLI3-190*|​S849_emp|​S880_unk|​active@Primary Cilium map
  13. GLI3-190*|​unk|​active@Nucleus map → map GLI3-190*|​ubi|​ubi|​ubi|​ubi@Nucleus map
  14. CDK8:​Core_promoter*:​CyclinC*:​MED12:​MED13:​Mediator*@Nucleus map + CBP*@Nucleus map + gpromoter_region@Nucleus map + GLI3-190*|​unk|​active@Nucleus map → map CBP*:​CDK8:​Core_promoter*:​CyclinC*:​GLI3-190*:​MED12:​MED13:​Mediator*:​promoter_region@Nucleus map
  15. gpromoter_region@Nucleus map + GLI3-190*|​unk|​active@Nucleus map → map GLI3-190*:​promoter_region@Nucleus map
  16. GLI3-190*|​unk|​active@Nucleus map → map GLI3-190*|​unk|​pho|​active@Nucleus map
  17. 14-3-3*@Nucleus map + GLI3-190*|​unk|​pho|​active@Nucleus map → map su_shh1_s_shh2_s113
As Catalyser:
  1. GLI3-190*|​S849_pho|​S868_pho|​S907_pho|​S873_pho|​S852_pho|​S865_pho|​S877_pho|​S903_pho|​S860_pho|​S880_pho|​S910_pho|​S1006_pho|​S980_pho|​ubi|​ubi|​ubi|​ubi@Proteosome map → map GLI3-83_sub_TRUNC_endsub_*@Cytosol map
  2. gCyclinD*@Nucleus map → map rCyclinD*@Nucleus map