Gene GLI1 map

Identifiers
HUGO:GLI1
Gli family zinc finger 1
HUGO:GLI1 HGNC:4317 ENTREZ:2735 UNIPROT:P08151 GENECARDS:GLI1 KEGG:2735 ATLASONC:GLIID310ch12q13 WIKI:GLI1

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
 Cancer Associated Fibroblasts  map  / GROWTH_FACTORS_SIGNALING_PATHWAYS  map
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / HEDGEHOG  map

References
CASCADE:HH
CASCADE:TGFB
PMID:20215540
Shh ligand induces expression of Gli1 mRNA in pancreatic CAFs
siRNA knockdown of SMO expression blocks GLI1 induction in pancreatic CAFs
PMID:17638910
GLI1, GLI2, GLI3 proteins are expressed in fibroblasts, GLI1 and GLI2 expression is upregulated by TGFB via SMAD3
PMID:11001584

gGLI1@Nucleus

References
s_shh2_re51( Survival  map ):
PMID:9216996 PMID:16413481 PMID:17000779
ANNOTATION: it was shown that Med12 binds to Gli1 promoter

Modifications:
In compartment: Cytosol
  1. gGLI1@Cytosol map
In compartment: Nucleus
  1. gGLI1@Nucleus map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. gGLI1@Cytosol map → map rGLI1@Cytosol map
    2. gGLI1@Nucleus map → map rGLI1@Nucleus map
    As Catalyser: