Protein Mediator* map

Maps_Modules
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / HEDGEHOG  map

References
PMID:21330129
ANNOTATION: Mediator consists of more than 20 subunits and can also excists as an holoenzyme. Therefore Mediator is depicted as one simple protein to reduce complexity.

Modifications:
Participates in complexes:
In compartment: Nucleus
  1. CDK8:​Core_promoter*:​CyclinC*:​MED12:​MED13:​Mediator*@Nucleus map
  2. CBP*:​CDK8:​Core_promoter*:​CyclinC*:​GLI3-190*:​MED12:​MED13:​Mediator*:​promoter_region@Nucleus map
Participates in reactions:
As Reactant or Product:
  1. CDK8:​Core_promoter*:​CyclinC*:​MED12:​MED13:​Mediator*@Nucleus map + CBP*@Nucleus map + gpromoter_region@Nucleus map + GLI3-190*|​unk|​active@Nucleus map → map CBP*:​CDK8:​Core_promoter*:​CyclinC*:​GLI3-190*:​MED12:​MED13:​Mediator*:​promoter_region@Nucleus map
As Catalyser:
  1. gGLI1@Nucleus map → map rGLI1@Nucleus map