Protein CDK8
Identifiers
Cyclin-dependent kinase 8
HUGO:CDK8 HGNC:1779 ENTREZ:1024 UNIPROT:P49336 GENECARDS:CDK8 REACTOME:69456 KEGG:1024 ATLASONC:GC_CDK8 WIKI:CDK8
Maps_Modules
HMC:EVADING_GROWTH_SUPPRESSORS
Survival
/ HEDGEHOG
References
PMID:21327159
PMID:21330129
Cyclin-dependent kinase
Modifications:
Participates in complexes:
In compartment: Nucleus
- CDK8:Core_promoter*:CyclinC*:MED12:MED13:Mediator*@Nucleus
- CBP*:CDK8:Core_promoter*:CyclinC*:GLI3-190*:MED12:MED13:Mediator*:promoter_region@Nucleus
Participates in reactions:
As Reactant or Product:- CDK8:Core_promoter*:CyclinC*:MED12:MED13:Mediator*@Nucleus
+ CBP*@Nucleus
+ gpromoter_region@Nucleus
+ GLI3-190*|unk|active@Nucleus
→
CBP*:CDK8:Core_promoter*:CyclinC*:GLI3-190*:MED12:MED13:Mediator*:promoter_region@Nucleus
As Catalyser:- gGLI1@Nucleus
→
rGLI1@Nucleus