Protein LRDD map

Identifiers
p53-induced death domain protein
HUGO:PIDD HGNC:16491 ENTREZ:55367 UNIPROT:Q9HB75

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / APOPTOSIS  map
 Regulated Cell Death  map  / CASPASES  map
 Regulated Cell Death  map  / DNA_DAMAGE_RESPONSE  map
 Regulated Cell Death  map  / MOMP_REGULATION  map

References
synonym:PIDD

LRDD@Nucleus

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / APOPTOSIS  map
 Regulated Cell Death  map  / CASPASES  map
 Regulated Cell Death  map  / DNA_DAMAGE_RESPONSE  map
 Regulated Cell Death  map  / MOMP_REGULATION  map

References
rc_re1402( Regulated Cell Death  map ):
PMID:19203584
involvment of CRADD is doubtful

LRDD@Cytosol

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / APOPTOSIS  map
 Regulated Cell Death  map  / CASPASES  map
 Regulated Cell Death  map  / DNA_DAMAGE_RESPONSE  map
 Regulated Cell Death  map  / MOMP_REGULATION  map

References
rc_re1152( Regulated Cell Death  map ):
PMID:11399776
in vitro by CASP3 and to a lesser extent by CASP7
PMID:15073321
by LRDD and CRADD

Modifications:
In compartment: Cytosol
  1. LRDD@Cytosol map
In compartment: Nucleus
  1. LRDD@Nucleus map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. rLRDD@Nucleus map → map LRDD@Cytosol map
    As Catalyser:
    1. Caspase2*@Cytosol map → map cleaved~Caspase2*@Cytosol map
    2. Caspase2*|​S122_pho@Nucleus map → map cleaved~Caspase2*@Nucleus map