Complex RHOB:RhoB_cytoskeletal_effectors* map
Complex composition:

  1. RhoB_cytoskeletal_effectors* map
  2. RHOB map


RHOB:​RhoB_cytoskeletal_effectors*@Cytosol

Identifiers
NAME:RHOB:RhoB_cytoskeletal_effectors*

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence  map  / EMT_REGULATORS  map
 EMT Senescence  map  / CELL_CELL_ADHESIONS  map
 EMT Senescence  map  / TIGHT_JUNCTIONS  map
 EMT Senescence  map  / CYTOSKELETON_POLARITY  map

References
Once activated, the GTPases bind to a spectrum of effectors to stimulate downstream signaling pathways.
RhoB binding to DIAPH1, DIAPH2 and RHPN2 leads to actin polymerization and cytoskeleton rearrangements, and also regulates endosomal trafficking.
PRK1 and RTKN are also RhoB downstream effectors.
RhoB can directly bind to PLCE1 and stimulate its enzymatic activity.


Modifications:
Participates in complexes:
In compartment: Cytosol
  1. RHOB:​RhoB_cytoskeletal_effectors*@Cytosol map
Participates in reactions:
As Reactant or Product:
  1. RHOB:​RhoB_cytoskeletal_effectors*@Cytosol map map Cytoskeleton remodeling@Nucleus map
  2. RHOB:​RhoB_cytoskeletal_effectors*@Cytosol map map Actin polymerization@Nucleus map
  3. em_emtc_emtc_s2942 + RhoB_cytoskeletal_effectors*@Cytosol map map RHOB:​RhoB_cytoskeletal_effectors*@Cytosol map
As Catalyser: