Protein LIG3 map

Identifiers
Ligase III DNA, ATP-dependent
HUGO:LIG3, HGNC:6600, ENTREZ:3980, UNIPROT:P49916

Maps_Modules
HMC:GENOME_INSTABILITY_AND_MUTATION
 Cell Cycle DNA Repair  map  / BER  map
 Cell Cycle DNA Repair  map  / A_NHEJ  map
 Cell Cycle DNA Repair  map  / NER  map

References
For BER:
PMID:15703371, PMID:19847258, PMID:16697054, PMID:14726013, PMID:20056333
For NER:
PMID:20211143, PMID:19809470, PMID:15703371, PMID:19847258, PMID:16697054, PMID:12648680, PMID:17884153, PMID:11900249
For A_NHEJ (alt_NHEJ or B_NHEJ or MMEJ):
PMID:21376743, PMID:24050180, PMID:22743550
Activation of WRN in cancers
PMID:18524993

Modifications:
In compartment: Nucleus
  1. LIG3@Nucleus map
Participates in complexes:
In compartment: Nucleus
  1. LIG3:​WRN@Nucleus map
  2. LIG3:​XRCC1|​pho@Nucleus map
  3. LIG3:​PARP1|​PolyADPribose_unk|​pho:​XRCC1|​pho@Nucleus map
Participates in reactions:
As Reactant or Product:
  1. XRCC1|​pho@Nucleus map + LIG3@Nucleus map + PARP1|​PolyADPribose_unk|​pho@Nucleus map → map LIG3:​PARP1|​PolyADPribose_unk|​pho:​XRCC1|​pho@Nucleus map
  2. LIG3@Nucleus map + WRN@Nucleus map → map LIG3:​WRN@Nucleus map
  3. LIG3@Nucleus map + XRCC1|​pho@Nucleus map → map LIG3:​XRCC1|​pho@Nucleus map
As Catalyser:
  1. gA_NHEJ_DNA_st5*@Nucleus map → map gA_NHEJ_DNA_st6*@Nucleus map
  2. gTC-NER_GG-NER_DNA_st5*@Nucleus map → map gTC-NER_GG-NER_DNA_st6*@Nucleus map
  3. gShP_BER_M-glyc_st5_B-glyc_DNA_st5*@Nucleus map → map gShP_BER_M-glyc_st5_B-glyc_DNA_st6*@Nucleus map