Identifiers
GNAS complex locus
GNAS1, "guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1"
HUGO:GNAS HGNC:4392 ENTREZ:2778 UNIPROT:O95467 GENECARDS:GNAS KEGG:2778 ATLASONC:GNASID40727ch20q13 WIKI:GNAS

Maps_Modules
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival   / WNT_NON_CANONICAL 

1. GTP:​G_alpha__sub_s_endsub_*@Cytoplasm
2. GDP:​G_alpha__sub_s_endsub_*:​G_beta_*:​G_gamma_*@Cytoplasm
3. G_alpha__sub_s_endsub_*:​G_beta_*:​G_gamma_*:​LRP6@Cytoplasm
4. G_alpha__sub_s_endsub_*:​G_beta_*:​G_gamma_*:​LRP6:​PTH@Cytoplasm
5. GTP:​G_alpha__sub_s_endsub_*:​G_beta_*:​G_gamma_*:​LRP6|​S1544_pho|​T1548_pho@Cytoplasm

1. GDP:​G_alpha__sub_s_endsub_*:​G_beta_*:​G_gamma_*@Cytoplasm + LRP6@Cytoplasm → G_alpha__sub_s_endsub_*:​G_beta_*:​G_gamma_*:​LRP6@Cytoplasm
2. PTH@default + G_alpha__sub_s_endsub_*:​G_beta_*:​G_gamma_*:​LRP6@Cytoplasm + GTP@Cytoplasm → G_alpha__sub_s_endsub_*:​G_beta_*:​G_gamma_*:​LRP6:​PTH@Cytoplasm + GDP@Cytoplasm
3. G_alpha__sub_s_endsub_*:​G_beta_*:​G_gamma_*:​LRP6:​PTH@Cytoplasm → GTP:​G_alpha__sub_s_endsub_*@Cytoplasm + LRP6@Cytoplasm + G_beta_*:​G_gamma_*@Cytoplasm + PTH@default
4. LRP6|​S1544_pho|​T1548_pho@Cytoplasm + GDP:​G_alpha__sub_s_endsub_*:​G_beta_*:​G_gamma_*@Cytoplasm + GTP@Cytoplasm → GTP:​G_alpha__sub_s_endsub_*:​G_beta_*:​G_gamma_*:​LRP6|​S1544_pho|​T1548_pho@Cytoplasm + GDP@Cytoplasm + LRP6|​S1544_pho|​T1548_pho@Cytoplasm
5. GTP:​G_alpha__sub_s_endsub_*:​G_beta_*:​G_gamma_*:​LRP6|​S1544_pho|​T1548_pho@Cytoplasm → GTP:​G_alpha__sub_s_endsub_*@Cytoplasm + GDP:​G_alpha__sub_s_endsub_*:​G_beta_*:​G_gamma_*@Cytoplasm
6. GTP:​G_alpha__sub_s_endsub_*@Cytoplasm + G_beta_*:​G_gamma_*@Cytoplasm → GDP:​G_alpha__sub_s_endsub_*:​G_beta_*:​G_gamma_*@Cytoplasm

1. GDP:​G_alpha__sub_s_endsub_*:​G_beta_*:​G_gamma_*@Cytoplasm + LRP6@Cytoplasm → G_alpha__sub_s_endsub_*:​G_beta_*:​G_gamma_*:​LRP6@Cytoplasm
2. Adenylyl_cyclase*@Cytoplasm → Adenylyl_cyclase*@Cytoplasm