Identifiers
NAME:ARHGAP35:RASA1
Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
EMT Senescence / EMT_REGULATORS
EMT Senescence / TIGHT_JUNCTIONS
EMT Senescence / CYTOSKELETON_POLARITY
References
PMID:8360177
RASA1 is a GAP for HRAS.
PMID:18829532
RasGAP actvity of RASA1 is reduced when associated with ARHGAP35 which is a specific GAP for RhoA
ARHGAP35 is tyrosine-phosphorylated.
The association of ARHGAP35 (p190) with RASA1 (p120) is promoted and stabilized by phosphorylation of p190 at Y1105 by PTK6..