Protein TUCAN* map

Identifiers
caspase recruitment domain family, member 8
HUGO:CARD8 HGNC:17057 ENTREZ:22900 UNIPROT:Q9Y2G2
Caspase recruitment domain family 8
HUGO:CARD8 HGNC:17057 ENTREZ:22900 UNIPROT:Q9Y2G2 GENECARDS:CARD8 KEGG:22900 ATLASONC:CARD8ID913ch19q13 WIKI:CARD8

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / DEATH_RECEPTOR_PATHWAYS  map
 Regulated Cell Death  map  / DEPENDANCE_RECEPTORS  map
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / HEDGEHOG  map

References
PMID:19465923
PMID:11408476
TUCAN was proposed to function as an adaptor protein for caspase-9

TUCAN*@Cytosol

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / DEATH_RECEPTOR_PATHWAYS  map
 Regulated Cell Death  map  / DEPENDANCE_RECEPTORS  map

References
rc_re1702( Regulated Cell Death  map ):
PMID:19465923
in the absence of Shh, Ptc recruits a protein complex that includes DRAL, one of the caspase recruitment (CARD)-domain containing proteins TUCAN (family member, 8) or NALP1 (NLR family, pyrin domain containing 1) and apical caspase-9

Modifications:
In compartment: Cytosol
  1. TUCAN*@Cytosol map
Participates in complexes:
In compartment: Cytosol
  1. DRAL*:​NEDD4:​NLRP1:​TUCAN*@Cytosol map
Participates in reactions:
As Reactant or Product:
  1. PTCH*@Cytosol map + DRAL*@Cytosol map + TUCAN*@Cytosol map + NLRP1@Cytosol map + NEDD4@Cytosol map → map DRAL*:​NEDD4:​NLRP1:​TUCAN*@Cytosol map
  2. PTCH*@Cytosol map + DRAL*@Cytosol map + TUCAN*@Cytosol map + Caspase9*@Cytosol map → map su_shh1_s_shh3_s137
As Catalyser:
  1. Caspase9*@Cytosol map → map Caspase9*|​K63_ubi@Cytosol map