Protein PLAUR map

Identifiers
plasminogen activator, urokinase receptor
HUGO:PLAUR hgnc_id:HGNC:9053 HGNC:9053 ENTREZ:5329 UNIPROT:Q03405

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
 Cancer Associated Fibroblasts  map  / INFLAMMATORY_SIGNALING_PATHWAYS  map

References
CASCADE:PLAU
PMID:27216177
FAP as a persistent activator of fibroblastic STAT3 through a uPAR-dependent FAK-Src-JAK2 signaling pathway.

Modifications:
In compartment: Cytosol
  1. PLAUR@Cytosol map
Participates in complexes:
In compartment: Cytosol
  1. PLAUR:​gp130*|​Y759_pho@Cytosol map
  2. JAK1|​pho:​PLAU:​PLAUR:​gp130*|​Y759_pho@Cytosol map
Participates in reactions:
As Reactant or Product:
  1. gp130*@Cytosol map + PLAUR@Cytosol map → map PLAUR:​gp130*|​Y759_pho@Cytosol map
  2. PLAU@default map + PLAUR:​gp130*|​Y759_pho@Cytosol map + JAK1|​pho@Cytosol map → map JAK1|​pho:​PLAU:​PLAUR:​gp130*|​Y759_pho@Cytosol map
As Catalyser:
  1. PTK2@Cytosol map → map PTK2|​pho@Cytosol map
  2. ITGB5@Cytosol map → map ITGB5|​ubi@Cytosol map