Phenotype Growth arrest map
Growth arrest@Cytoplasm

Maps_Modules
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / MAPK  map

References
Growth Arrest
su_mpk1_mpk1_re250( Survival  map ):
CHOP/GADD153 (DDIT3) mediates in part cell cycle arrest at G1/S an important consequence of DNA damage. It is phosphorylated by P38.
PMID:11274345
su_mpk1_mpk1_re278( Survival  map ):
Cell growth arrest is induced by STAT1 through cyclin-dependent kinase inhibitor P21 WAF1/CIP1.
PMID:8614832

Modifications:
In compartment: Cytoplasm
  1. Growth arrest@Cytoplasm map
In compartment: Nucleus
  1. Growth arrest@Nucleus map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. DDIT3|​pho@Nucleus map → map Growth arrest@Cytoplasm map
    2. p21CIP1*@Nucleus map → map Growth arrest@Cytoplasm map
    3. JUN@Nucleus map → map Growth arrest@Nucleus map
    4. JUNB@Nucleus map → map Growth arrest@Nucleus map
    As Catalyser: