Complex ARF6:DNM2_GTP:NME2 map
Complex composition:

  1. NME2 map
  2. ARF6 map
  3. DNM2_GTP map

ARF6:​DNM2_GTP:​NME2@Cytosol

Identifiers
NAME:ARF6:DNM2_GTP:NME2

References
PMID:12447393
Activation of (activated) ARF6 is required for dynamin-dependent endocytosis of E-cadherin.
Nm23-H1 binds ARF6-GTP and mediates dynamin-dependent vesicle fission. (I has not however be tested wheter, NM23H2 (NME2) binds ARF6 as well, nut is is strongly suggested)
PMID:25234227
Dynamin 2 act on the actin cytoskeleton by:
- Promoting membrane remodeling and endocytosis of cell receptor thanks to NDPKA (NME1) and NDPKB (NME2)
em_re1432( EMT Senescence  map ):
DNM2 induces E-cadherin internalisation

Modifications:
Participates in complexes:
In compartment: Cytosol
  1. ARF6:​DNM2_GTP:​NME2@Cytosol map
Participates in reactions:
As Reactant or Product:
  1. em_s2267 → map ARF6:​DNM2_GTP:​NME2@Cytosol map
  2. ARF6@Cytosol map → map ARF6:​DNM2_GTP:​NME2@Cytosol map
  3. NME2@Cytosol map → map ARF6:​DNM2_GTP:​NME2@Cytosol map
As Catalyser:
  1. Clathrin Coated pit@Cytosol map → map Clathrin dependent endosomal pathway@Clathrin coated vesicle map