Complex GPCR*:GRK* map
Complex composition:

  1. GRK* map
  2. GPCR* map

GPCR*|​pho:​GRK*@Plasma Membrane

Identifiers
NAME:GPCR*:GRK*

References
su_mpk1_mpk1_re85( Survival  map ):
Recruited GRKs (GRK2 and GRK3) phosphorylate GPCR and increase its affinity for binding beta-ARRESTIN.
PMID:11226259

GPCR*:​GRK*@Early Endosomes

Identifiers
NAME:GPCR*:GRK*

References
su_mpk1_mpk1_re86( Survival  map ):
The internalised GPCR receptor will finally be recycled into the cell membrane or be sent to lysosome for degradation (not modelled).
PMID:19565474

Modifications:
Participates in complexes:
In compartment: Early Endosomes
  1. GPCR*:​GRK*@Early Endosomes map
In compartment: Plasma Membrane
  1. GPCR*|​pho:​GRK*@Plasma Membrane map
Participates in reactions:
As Reactant or Product:
  1. GPCR*|​pho:​GRK*@Plasma Membrane map + _beta_-Arrestin2*@Cytoplasm map → map GPCR*|​pho:​GRK*:​_beta_-Arrestin2*@Plasma Membrane map
  2. GPCR*@Plasma Membrane map + GRK*@Cytoplasm map → map GPCR*|​pho:​GRK*@Plasma Membrane map
  3. ERK*|​pho|​pho:​GPCR*:​GRK*:​MEK*|​pho|​pho:​RAF1|​pho:​_beta_-Arrestin2*@Early Endosomes map → map GPCR*:​GRK*@Early Endosomes map + ERK*|​pho|​pho:​MEK*|​pho|​pho:​_beta_-Arrestin2*@Early Endosomes map + RAF1@Cytoplasm map
As Catalyser: