Protein ITPR* map

Identifiers
inositol 1,4,5-trisphosphate receptor type 1
HUGO:ITPR1 hgnc_id:HGNC:6180 HGNC:6180 ENTREZ:3708 UNIPROT:Q14643
inositol 1,4,5-trisphosphate receptor type 2
HUGO:ITPR2 hgnc_id:HGNC:6181 HGNC:6181 ENTREZ:3709 UNIPROT:Q14571
inositol 1,4,5-trisphosphate receptor type 3
HUGO:ITPR3 hgnc_id:HGNC:6182 HGNC:6182 ENTREZ:3710 UNIPROT:Q14573

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / ER_STRESS  map

References
PMID:23850759

Modifications:
In compartment: Cytosol
  1. ITPR*@Cytosol map
In compartment: Endopasmic Reticulum
  1. ITPR*@Endopasmic Reticulum map
Participates in complexes:
In compartment: Endopasmic Reticulum
  1. BiP*:​Ca2+:​Grp75*:​ITPR*:​SIGMAR1:​VDAC*@Endopasmic Reticulum map
Participates in reactions:
As Reactant or Product:
  1. ITPR*@Endopasmic Reticulum map → map low Ca2+ level@Endopasmic Reticulum map
  2. Grp75*@Endopasmic Reticulum map + BiP*:​SIGMAR1@Endopasmic Reticulum map + Ca2+@Endopasmic Reticulum map + ITPR*@Cytosol map + VDAC*@Cytosol map → map BiP*:​Ca2+:​Grp75*:​ITPR*:​SIGMAR1:​VDAC*@Endopasmic Reticulum map
  3. ITPR1 @Endopasmic Reticulum map → map ITPR*@Endopasmic Reticulum map
  4. ITPR2@Endopasmic Reticulum map → map ITPR*@Endopasmic Reticulum map
  5. ITPR3@Endopasmic Reticulum map → map ITPR*@Endopasmic Reticulum map
  6. ITPR*@Endopasmic Reticulum map → map ITPR*@Endopasmic Reticulum map
As Catalyser:
  1. Ca2+@Endopasmic Reticulum map → map BiP*:​Ca2+:​Grp75*:​ITPR*:​SIGMAR1:​VDAC*@Endopasmic Reticulum map
  2. Ca2+@Endopasmic Reticulum map → map Ca2+@Cytosol map