Protein CRADD map

Identifiers
HUGO:CRADD
CASP2 and RIPK1 domain containing adaptor with death domain
HUGO:CRADD HGNC:2340 ENTREZ:8738 UNIPROT:P78560

Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Adaptive Immune Response  map  / TCR_SIGNALING  map
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / APOPTOSIS  map
 Regulated Cell Death  map  / CASPASES  map
 Regulated Cell Death  map  / MOMP_REGULATION  map

References
PMID:22323537

CRADD@Cytosol

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / APOPTOSIS  map
 Regulated Cell Death  map  / CASPASES  map
 Regulated Cell Death  map  / MOMP_REGULATION  map

References
rc_re1152( Regulated Cell Death  map ):
PMID:11399776
in vitro by CASP3 and to a lesser extent by CASP7
PMID:15073321
by LRDD and CRADD

Modifications:
In compartment: Cytosol
  1. CRADD@Cytosol map
In compartment: T_cell
  1. CRADD@T_cell map
Participates in complexes:
In compartment: T_cell
  1. BCL10:​CRADD@T_cell map
Participates in reactions:
As Reactant or Product:
  1. BCL10@T_cell map + CRADD@T_cell map → map BCL10:​CRADD@T_cell map
  2. BCL10:​CRADD@T_cell map → map degraded
As Catalyser:
  1. Caspase2*@Cytosol map → map cleaved~Caspase2*@Cytosol map