Identifiers
NAME:BRIT1*:E2F1
Maps_Modules
HMC:SUSTAINING_PROLIFERATIVE_SIGNALLING
Cell Cycle DNA Repair / S_PHASE_CHECKPOINT
Cell Cycle DNA Repair / G2_M_CHECKPOINT
References
BRIT1*/E2F1 complex activates BRCA1 and CHEK1 transcription during S-phase and G2/M checkpoints
PMID:15220350, PMID:18660752
ce_re488( Cell Cycle DNA Repair ):
PMID:15220350, PMID:18660752, PMID:20376879
ce_re232( Cell Cycle DNA Repair ):
p53 inhibits BRCA1 expression, this is a negative loop as response to the up-regulation and stabilization of p53 by BRCA1:
PMID:10884389, PMID:12496474