Protein BAG6 map

Identifiers
HUGO:BAG6

Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Adaptive Immune Response  map  / INHIBITING_CHECKPOINTS  map

References
PMID:27192565 PMID:22863785
 NATURAL_KILLER  map
CASCADE:NKP30
PMID:23414611, PMID:18055229
BAG6 (BAT3) is a NKp30 ligand expressed on tumor cells. ??NKp30 recognises BAG6, which leads to NK cell killing of the tumour cell.

BAG6@TUMOR_CELL_AS_INDUCTOR_Membrane

References
in_re159( Innate Immunity  map ):
PMID:11062502, PMID:15536084
ERK1/2 activation induces perforin and granzyme B movement towards target tumor cells downstream of PI3K signaling in NK cells.

Modifications:
In compartment: TUMOR_CELL_AS_INDUCTOR
  1. BAG6@TUMOR_CELL_AS_INDUCTOR map
In compartment: TUMOR_CELL_AS_INDUCTOR_Membrane
  1. BAG6@TUMOR_CELL_AS_INDUCTOR_Membrane map
In compartment: T_cell
  1. BAG6@T_cell map
Participates in complexes:
In compartment: T_cell
  1. BAG6:​HAVCR2@T_cell map
Participates in reactions:
As Reactant or Product:
  1. BAG6:​HAVCR2@T_cell map + FYN@T_cell map → map FYN:​HAVCR2|​pho@T_cell map + BAG6@T_cell map
  2. rBAG6@TUMOR_CELL_AS_INDUCTOR map → map BAG6@TUMOR_CELL_AS_INDUCTOR map
  3. BAG6@TUMOR_CELL_AS_INDUCTOR map → map BAG6@TUMOR_CELL_AS_INDUCTOR_Membrane map
As Catalyser:
  1. LCK@cSMAC map + CD4@cSMAC map → map CD4:​LCK|​Y394_pho@cSMAC map
  2. LCK@cSMAC map + CD8*@cSMAC map → map CD8*:​LCK|​Y394_pho@cSMAC map
  3. CD247:​NKp30*@INNATE_IMMUNE_CELL_Membrane map → map CD247|​pho:​NKp30*@INNATE_IMMUNE_CELL_Membrane map