Protein ARHGAP14* map

Identifiers
SLIT-ROBO Rho GTPase activating protein 3
"SLIT-ROBO Rho GTPase activating protein 2", SRGAP2
HUGO:SRGAP3 HGNC:19744 ENTREZ:9901 UNIPROT:O43295

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence  map  / EMT_REGULATORS  map
 EMT Senescence  map  / CYTOSKELETON_POLARITY  map

ARHGAP14*@Cytosol

References
em_emtc_emtc_re893( EMT Senescence  map ):
PMID:8836113
GEFs are essential for CDC42 activation. They promote the exchange of GDP to GTP to generate the activated form of CDC42 capable of recognizing downstram targets.
PMID:11889037
ARHGAP14 (MCF2L or DBS) as a GEF of CDC42

Modifications:
In compartment: Cytosol
  1. ARHGAP14*@Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. Rac1_GAPs*@Cytosol map → map ARHGAP14*@Cytosol map
    2. CDC42_GEFs*@Cytosol map → map ARHGAP14*@Cytosol map
    As Catalyser: