Protein DEF6 map

Identifiers
differentially expressed in FDCP 6 homolog (mouse)
HUGO:DEF6 HGNC:2760 ENTREZ:50619 UNIPROT:Q9H4E7

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence  map  / EMT_REGULATORS  map
 EMT Senescence  map  / CYTOSKELETON_POLARITY  map

DEF6@Cytosol

References
em_emtc_emtc_re892( EMT Senescence  map ):
PMID:8836113
GEFs are essential for CDC42 activation. They promote the exchange of GDP to GTP to generate the activated form of CDC42 capable of recognizing downstram targets.
PMID:15023524
DEF6 as a GEF of CDC42

Modifications:
In compartment: Cytosol
  1. DEF6@Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. Rac1_GEFs*@Cytosol map → map DEF6@Cytosol map
    2. CDC42_GEFs*@Cytosol map → map DEF6@Cytosol map
    As Catalyser: