Antisense RNA MIR34A map

Identifiers
microRNA 34a
HUGO:MIR34A, HGNC:31635, ENTREZ:407040, GENECARDS:GC01M009211
HUGO:MIR34A HGNC:31635 ENTREZ:407040
HUGO:MIR34A
HUGO:MIR34A HGNC:31635 ENTREZ:407040 GENECARDS:MIR34A KEGG:407040 ATLASONC:GC_MIR34A WIKI:MIR34A

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence  map  / EMT_REGULATORS  map
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / WNT_CANONICAL  map

References
PMID:20351093
PMID:22363487
 NATURAL_KILLER  map
PMID:22102694
Tumor suppressive microRNAs miR-34a/c control cancer cell expression of ULBP2, a stress-induced ligand of the natural killer cell receptor NKG2D.
Activation of p53 by Nutlin3a resulted in upregulation of Mir34a/c expression.

arMIR34A@Nucleus

References
em_emtc_emtc_re365( EMT Senescence  map ):
PMID:20351093
PMID:17823410
PMID:22134354
PMID:22160706

arMIR34A@Cytosol

References
rc_re141( Regulated Cell Death  map ):
PMID:17554199
by p53
PMID:17656095
PMID:17540599
PMID:17554337
PMID:19696787
in TIG3 TERT/??B-RAF:ER, by ELK1 (siRNA ELK1 and MIR34A PCR; ChIP)
in HEK293 by ELK1, gene reporter
rc_re105( Regulated Cell Death  map ):
PMID:16166262
PMID:23070007
in chronic lymphocytic leukemia human cells
rc_re156( Regulated Cell Death  map ):
PMID:17942906
in Burkitt lymphoma cells
PMID:9804616
in human rhabdomyosarcoma Rh30 but not Rh1 cells, rapamycin inhibits serum-induced expression of MYC
rc_re235:( Regulated Cell Death  map ) PMID:17297439
rc_re1121( Regulated Cell Death  map ):
PMID:19960022
by MIR34A and MIR449A
PMID:18755897
by MIR34A
PMID:20185821

Modifications:
In compartment: Cytosol
  1. arMIR34A@Cytosol map
In compartment: Nucleus
  1. arMIR34A@Nucleus map
In compartment: TUMOR_CELL_AS_INDUCTOR
  1. arMIR34A@TUMOR_CELL_AS_INDUCTOR map
Participates in complexes:
In compartment: Cytosol
  1. JAG1:​MIR34A@Cytosol map
  2. MIR34A:​NOTCH1@Cytosol map
  3. BMI1:​Cyclin D1*@Cytosol map
In compartment: Nucleus
  1. AXIN2:​MIR34A@Nucleus map
Participates in reactions:
As Reactant or Product:
  1. gMIR34A@Nucleus map → map arMIR34A@Nucleus map
  2. gMIR34A@TUMOR_CELL_AS_INDUCTOR map → map arMIR34A@TUMOR_CELL_AS_INDUCTOR map
  3. gMIR34A@Nucleus map → map arMIR34A@Cytosol map
  4. arMIR34A@Cytosol map → map arMIR34*@Cytosol map
  5. arMIR34A@Nucleus map + rAXIN2@Nucleus map → map AXIN2:​MIR34A@Nucleus map
  6. gMIR34A@Nucleus map → map arMIR34A@Nucleus map
  7. arMIR34A@Nucleus map + rLEF1@Nucleus map → map LEF1:​MI34*@Nucleus map
  8. arMIR34A@Nucleus map + rWNT1@Nucleus map → map MI34*:​WNT1@Nucleus map
  9. arMIR34A@Nucleus map + rWNT3@Nucleus map → map MI34*:​WNT3@Nucleus map
  10. arMIR34A@Nucleus map + rLRP6@Nucleus map → map LRP6:​MI34*@Nucleus map
  11. arMIR34A@Nucleus map + r_beta_-Catenin*@Nucleus map → map MI34*:​_beta_-Catenin*@Nucleus map
As Catalyser:
  1. rULBP2@TUMOR_CELL_AS_INDUCTOR map → map ULBP2@TUMOR_CELL_AS_INDUCTOR map
  2. rBCL2@Nucleus map → map BCL2@Cytosol map
  3. rSIRT1@Nucleus map → map SIRT1@Cytosol map
  4. rCDK6@Nucleus map → map CDK6@Nucleus map
  5. rMYC@Nucleus map → map MYC@Nucleus map
  6. rE2F3A*@Nucleus map → map E2F3@Cytosol map