Complex IL6R:JAK1:JAK2:TYK2:gp130* map
Complex composition:

  1. JAK2 map
  2. TYK2 map
  3. JAK1 map
  4. IL6R map
  5. gp130* map

IL6R:​JAK1|​pho:​JAK2|​pho:​TYK2|​pho:​gp130*|​Y759_pho@Cytosol

Identifiers
NAME:IL6R:JAK1:JAK2:TYK2:gp130*

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
 Cancer Associated Fibroblasts  map  / INFLAMMATORY_SIGNALING_PATHWAYS  map

References
PMID:1439146
IL6 signaling acts through IL6 receptor and receptor-associated signal transducer, gp130
PMID:22595692
The structure of receptors of IL6 like cytokines
9716487??
IL6 signaling acts through jak/stat pathway, probably via Jak1, Jak2 and Tyk2

Modifications:
Participates in complexes:
In compartment: Cytosol
  1. IL6R:​JAK1|​pho:​JAK2|​pho:​TYK2|​pho:​gp130*|​Y759_pho@Cytosol map
Participates in reactions:
As Reactant or Product:
  1. IL6R:​gp130*|​Y759_pho@Cytosol map + JAK1|​pho@Cytosol map + TYK2|​pho@Cytosol map + JAK2|​pho@Cytosol map → map IL6R:​JAK1|​pho:​JAK2|​pho:​TYK2|​pho:​gp130*|​Y759_pho@Cytosol map
As Catalyser:
  1. STAT3@Cytosol map → map STAT3|​pho@Cytosol map