Reaction state_transition rc_re1172 map

p14ARF*@Nucleus map → p14ARF*|​ubi@Nucleus map

Reaction regulators:
Catalysis
  1. TRIP12@Nucleus map
Inhibition
  1. MYC@Nucleus map


References
PMID:20208519
TRIP12 is a E3 ubiquitin ligase for ARF
MYC, independently of its DNA binding domain, inhibits TRIP12-mediated ARF degradation through direct interaction with TRIP12
Nucleophosmin protects ARF from TRIP12-mediated ubiquitination by targeting it to the nucleolus