Identifiers
thyroid hormone receptor interactor 12
HUGO:TRIP12 HGNC:12306 ENTREZ:9320 UNIPROT:Q14669
Maps_Modules
HMC:RESISTING_CELL_DEATH
Regulated Cell Death / RCD_GENES
Maps_Modules
HMC:RESISTING_CELL_DEATH
Regulated Cell Death / RCD_GENES
References
rc_re1172( Regulated Cell Death ):
PMID:20208519
TRIP12 is a E3 ubiquitin ligase for ARF
MYC, independently of its DNA binding domain, inhibits TRIP12-mediated ARF degradation through direct interaction with TRIP12
Nucleophosmin protects ARF from TRIP12-mediated ubiquitination by targeting it to the nucleolus