Reaction state_transition rc_re1000 map

BCL2|​unk@Mitochondrial inner membrane map → cleaved~BCL2*@Mitochondrial inner membrane map

Reaction regulators:
Catalysis
  1. cleaved~Caspase3*@Cytosol map
Inhibition
  1. FKBP8@Mitochondrial inner membrane map


References
influenceDelete: reactants to re
hierarchical:post-MOMP
reactionType:casp.cleavage
PMID:10409669
CASP3 mediated cleavage of BCL2 in vitro and in HL60 cells or MCF7 with reconstituted CASP3 expression after exposure to staurosporine
no cleavage by CASP7
PMID:20139069
FKBP8 protects BCL2 from CASP3-mediated degradation