Phenotype Antibody-dependent cellular cytotoxicity
Antibody-dependent cellular cytotoxicity@Membrane
Identifiers
Maps_Modules
MODULE:MACROPHAGE
References
PMID:12413632
Both GM-CSF and M-CSF increase the cytokine production of
macrophages and antibody-dependent cellular cytotoxicity (ADCC).
PMID:9435247
Macrophage ADCC of tumor target cells requires Fc gamma R types I and III
Modifications:
In compartment: Membrane
- Antibody-dependent cellular cytotoxicity@Membrane
Participates in complexes:
Participates in reactions:
As Reactant or Product:- CSF2@default
→
Antibody-dependent cellular cytotoxicity@Membrane
- CSF1@default
→
Antibody-dependent cellular cytotoxicity@Membrane
- CD64*@Cytosol
→
Antibody-dependent cellular cytotoxicity@Membrane
- CD16*@Membrane
→
Antibody-dependent cellular cytotoxicity@Membrane
- Antibody-dependent cellular cytotoxicity@Membrane
→
Tumor cell death@default
As Catalyser: