Reaction state_transition re300 map

IRAK1@Cytosol map → IRAK1|​pho|​active@Cytosol map

Reaction regulators:
Catalysis
  1. CD14:​IRAK2:​IRAK4:​LY96:​MYD88:​TIRAP:​TLR2/4*@Membrane map





Identifiers

Maps_Modules

References
PMID:12620219
MyD88 mediates a close interaction of the two related IRAK molecules,
which is essential to allow IRAK-4 to phosphorylate IRAK-1. Phosphorylation of IRAK-1
reduces its affinity for MyD88, while increasing its affinity for TRAF6