Protein IRAK1 map

Identifiers
HUGO:IRAK1

Maps_Modules
MODULE:MACROPHAGE
MODULE:IMMUNOSTIMULATORY_CYTOKINE_PATHWAYS

References
PMID:12620219
MyD88 mediates a close interaction of the two related IRAK molecules,
which is essential to allow IRAK-4 to phosphorylate IRAK-1. Phosphorylation of IRAK-1
reduces its affinity for MyD88, while increasing its affinity for TRAF6.

IRAK1@Cytosol

Identifiers

Maps_Modules

References

IRAK1|​pho|​active@Cytosol

Identifiers

Maps_Modules

References

Modifications:
In compartment: Cytosol
  1. IRAK1@Cytosol map
  2. IRAK1|​pho|​active@Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. IRAK1@Cytosol map → map IRAK1|​pho|​active@Cytosol map
    As Catalyser:
    1. TRAF6@Cytosol map → map TRAF6@Cytosol map