Phenotype Antitumor activity
Antitumor activity@default
Identifiers
Maps_Modules
MODULE:MACROPHAGE
References
PMID:1431106
Classical activation of macrophages (M1) induces macrophage
tumoricidal activity
PMID:20338029
The M1 form of tumor-associated macrophages in tumor
is positively associated with survival time.
Modifications:
In compartment: default
- Antitumor activity@default
Participates in complexes:
Participates in reactions:
As Reactant or Product:- NO production@Cytosol
→
Antitumor activity@default
- ROS production@Cytosol
→
Antitumor activity@default
- Antitumor activity@default
→
Tumor cell death@default
- M1 phenotype of macrophages@Cytosol
→
Antitumor activity@default
As Catalyser: