Reaction transcription re125 map

gTGFB1@Cytosol map → rTGFB1@Cytosol map

Reaction regulators:
Catalysis
  1. FOSL2@Cytosol map
  2. JUND@Cytosol map
  3. FOS@Cytosol map
  4. CD14:​IRAK2:​IRAK4:​LY96:​MYD88:​TIRAP:​TLR2/4*@Membrane map
  5. IFNG|​hm2@default map
  6. JUN|​pho|​active@Cytosol map
  7. MYC@Cytosol map





Identifiers

Maps_Modules

References
PMID:16327802
IL13 and TNF together (but neither IL-13 nor TNF alone) upregulates TGFB1 expression downstream of IL13RA2.
IL13 and TNF inducese TGFB1 expression via AP-1 transcription factors.IL13 induces binding of c-jun and fra2 ti TGFB1 promotor, and TNF binding of c-jun, JunD and c-fos.
PMID:21372296
HMGB1 markedly increased the expression of the genes for VEGF, and TGFB1 in
peritoneal macrophages via TLR4-dependent mechanisms.